Monday, July 23, 2007

Sunscreen causes cancer???

According to this article, 84% of sunscreens are causing cancer and...

As NewsTarget readers have known for a long time, sunscreen products are a hoax, and they actually cause cancer instead of preventing it. The more consumers use sunscreen products, the greater their chance of someday being diagnosed with cancer. Part of this is due to sunscreen's effect of blocking ultraviolet radiation (UV light), which generates the powerful anti-cancer nutrient Vitamin D in human skin. Vitamin D is quite simply the world's best anti-cancer medicine, and recent studies have shown that it can prevent nearly four out of five cancers in women (ALL cancers, including breast cancer, cervical cancer, lung cancer, brain tumors, multiple myeloma and even skin cancer).


Three issues here...

1. UV light can damage skin. UV light damages cellular DNA and inhibits normal base-pairing. This can lead to mutations and neoplastic behavior. UV light has been proven over and over to be a cause of skin cancer. Further, patients with xeroderma pigmentosa, a genetic disorder where parts of the DNA's repair mechanism are mutated, have a high rate of skin cancer. This supports the assertion that UV-caused DNA damage can lead to skin cancer.

2. Dangers of sunscreen
The Australian government did an excellent review of the literature on potentially hazardous components of sunscreen. (Australia has the highest incidence of skin cancer, and coincidentally, is very interested in sunscreen.) Zinc oxide and titanium dioxide have been used in sunscreen for many years. They are broad spectrum UVA and UVB blockers, and are really a great choice for sun protection.
But because they are opaque, and it is no longer the 80s, people don't want to use them. The nanosized zinc oxide and titanium dioxide offer sun protection without the opacity. The concern is that the nano particles will be absorbed into the dermis and, with the application of light and heat, will become toxic.

I'm not going to reference each article individually, you can follow the link to the Australian document. But nanoparticles of titanium dioxide have been shown to produce OH radicals when exposed to UVA light. These OH radicals can harm viable cells, cause DNA mutations, and potentially lead to cancer, according to in vitro experiments. However, this has never been studied in vivo (in actual skin samples). It has only been studied in non-epidermal cells. The unique part about our epidermis is that the stratum corneum has a waxy layer that helps keep moisture in and toxins out. The epidermis is constantly regenerating, but the replicating cells are below the stratum corneum. So, as long as the nanoparticles do not go below the stratum corneum, our replicating cells are safe. And these replicating cells are the ones who are in danger of turning cancerous. A cancer is just a replicating cell that starts replicating out of control. All the studies examining how deep the nanoparticles penetrate show the same thing... THE NANOPARTICLES DO NOT PENETRATE PAST THE STRATUM CORNEUM. This means that they cannot cause cancer. One loophole is that hair follicles go all the way down past the epidermis into the dermis. But the studies looking at titanium dioxide penetration of hair follicles shows that the particles stay in the upper follicle and do not absorb into the dermis.

We need a study that uses human skin samples, micronized titanium dioxide, and sun exposure, and that tests for both penetration and cellular damage short term and skin cancer long term.

3. Vitamin D is good, but you don't need all that much sunlight to produce adequate amounts of it. UVB is involved in the production of vitamin D and then the kidneys and liver convert it to its active form. The Vitamin D then helps absorb calcium from the intestinal tract.

This study...

Valrance ME, Brunet AH, Welsh J.VDR Dependent Inhibition of Mammary Tumor Growth by EB1089 and UV Radiation in vivo.Endocrinology. 2007 Jul 12

... and many others like it, show that certain tumors containing vitamin D receptors do respond to vitamin D therapy. However, vitamin D does not prevent these tumors. It is being studied as a therapeutic (not preventative) agent for specific cancers with the specific receptor.

For now, I'm going to continue wearing my micronized titanium dioxide sunscreen.

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