Sweaty palms... treatment with botox

Botulinum toxin A blocks the release of the neurotransmitter acetylcholine at the neuromuscular junction. This toxin, which is produced by the Clostridium botulinum bacteria, inhibits the stimulation of muscular cells, including those surrounding eccrine sweat glands. Blocking the secretion of sweat glands in this way has proven to be an effective treatment usually lasting 3-4 months. It does, however, require multiple injections. With 1.5 cm standard spacing, my palms would need about 50 injections each.

Solish N, Bertucci V, Dansereau A, Hong HC, Lynde C, Lupin M, Smith KC, Storwick G; Canadian Hyperhidrosis Advisory Committee. A comprehensive approach to the recognition, diagnosis, and severity-based treatment of focal hyperhidrosis: recommendations of the Canadian Hyperhidrosis Advisory Committee. Dermatol Surg. 2007 Aug;33(8):908-23.